to support individuals with Down syndrome

7th Annual Relay and Run for 21 

Please stay tuned for information on 2018's

The third sunday of each march, come TACKLE 21 KILOMETERS ​(13.1 MILES) ON YOUR OWN OR AS PART OF A 3-PERSON RELAY TO HELP SUPPORT those with DS! OR TAKE PART IN THE 7K OR 2.1K!


The Relay and Run for 21 - held each year just before World Down Syndrome Day - helps to raise money for the  Down Syndrome Association of Greater St. Louis and DADS Community Outreach Fund. The 21 represents the third 21st chromosome, and 21 kilometers is the approximate distance for a half marathon. 


Events include a 21K (half marathon), a 21K 3-person relay, 7K run and 2.1K walk. New for 2017, the course will feature three loops through the streets of Clayton and U-City, with the start, finish and relay exchanges all taking place at Clayton High School. ​Race amenities include a race shirt, finisher medal and finish line food and more. For more, see our details page and course page